Experimental Infection of Ground Squirrels (Spermophilus tridecemlineatus) with Monkeypox Virus

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Experimental Infection of Ground Squirrels (Spermophilus tridecemlineatus) with Monkeypox Virus

A proposed new small-animal (rodent) model for studying the pathogenesis and treatment of severe orthopoxvirus infections is described. Thirteen-lined ground squirrels (Spermophilus tridecemlineatus) were infected intraperitoneally and intranasally with monkeypox virus (MPXV). A fulminant illness developed in all animals, and they died 6-9 days after infection. Virus was cultured from the blood...

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Sarcocystis campestris from naturally infected 13-lined ground squirrels, Spermophilus tridecemlineatus tridecemlineatus, from Nebraska.

Grossly visible sarcocysts were seen in the skeletal muscles of 1 of 12 13-lined ground squirrels, Spermophilus tridecemlineatus tridecemlineatus, collected in Nebraska. The tissue cyst wall was up to 5.0 microm thick and contained spikelike projections. Transmission electron microscopy of tissue cysts revealed they were similar to Sarcocystis campestris Cawthorn, Wobeser, and Gajadhar, 1983, p...

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Experimental infection of Richardson's ground squirrels (Spermophilus richardsonii) with attenuated and virulent strains of Brucella abortus.

A previous investigation of the safety of Brucella abortus strain RB51 (sRB51) in various nontarget species suggested that Richardson's ground squirrels (Spermophilus richardsonii) may develop persistent infections when orally inoculated with the vaccine. In the present study, sRB51, B. abortus strain 19 (s19), and virulent B. abortus strain 9941 (s9941) were administered orally to Richardson's...

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Experimental Infection of Richardson’s Ground Squirrels (Spermophilus Richardsonii ) With Attenuated and Virulent Strains pf Brucella abortus

A previous investigation of the safety of Brucella abortus strain RB51 (sRB51) in various nontarget species suggested that Richardson’s ground squirrels (Spermophilus richardsonii) may develop persistent infections when orally inoculated with the vaccine. In the present study, sRB51, B. abortus strain 19 (s19), and virulent B. abortus strain 9941 (s9941) were administered orally to Richardson’s...

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ژورنال

عنوان ژورنال: Emerging Infectious Diseases

سال: 2004

ISSN: 1080-6040,1080-6059

DOI: 10.3201/eid1009.040310